General Toxicity
JOINN’s toxicology study system covers the nonclinical safety assessment of drugs throughout their entire lifecycle, aiming to systematically characterize the toxicity profile and identify potential risks of drugs. The study design complies with international GLP regulations and has been accredited by China’s NMPA, US FDA, OECD, Korea’s MFDS, and Japan’s PMDA, as well as AAALAC animal welfare certification and CMA, etc. With 30 years of practical experience, the facility is well-versed in the regulatory requirements for drug evaluation across different countries and capable of customizing designs based on characteristics of drugs to reveal their toxicity profiles. JOINN is able to provide high-quality and comprehensive toxicology evaluation services to facilitate the smooth progress of drug development.
Services
Dose Range Finding Study
Acute Toxicity Study
Subacute Toxicity Study
Subchronic Toxicity Study
Chronic Toxicity Study
Animal Species
Rodents: Mice, Hamsters, Rats, Guinea Pigs
Non-rodents: Rabbits, Dogs, Miniature Pigs, Non-human Primates, etc.
Testing Sample Types
Traditional Chinese medicines, processed herbal slices, finished Chinese herbal products, Chinese and Western patent medicines, etc.
Chemical Raw materials and their formulations, antibiotics, etc.
Biochemical drugs, radioactive drugs, serum, vaccines, blood products, cell products, diagnostic drugs, etc.
Routes of Administration
In vivo Administration
Oral Administration
Injection Administration
Intramuscular Injection
Intraperitoneal Injection
Subcutaneous Injection
Intravenous Injection (Intravenous Bolus, Intravenous Infusion, Continuous Infusion)
In vitro Administration
Skin (Dermal Application/Application of Patches, Intradermal Injection)
Other Administration Methods
Special Ocular Routes of Administration (Conjunctival Sac, Vitreous Body, Retrobulbar Injection, Retinal Injection, etc.)
Inhalation Administration (Including Tracheal Administration)
Intranasal Administration
Vaginal Administration
Intracerebral Injection (Precise Site Administration Using Brain Stereotactic Instrument)
Intra-articular Injection
Spinal Injection
Subarachnoid Space (Intrathecal Injection, Continuous Infusion)
