Medical Devices
Safety and Efficacy Evaluation
Large Animal In Vivo Evaluation (FDA GLP, OECD GLP from European Countries)
a. Cardiothoracic Surgery/Cardiology
b. Orthopedics
c. Ophthalmology
d. Dentistry
e. Dermatology/Cosmetic Surgery
f. Neurosurgery/Brain Surgery
g. Drug-Device Combination Evaluation
h. Toxicological Testing of Aesthetic Injection Products
Category
Stable Models
Cardiovascular
Mitral/tricuspid/aortic/pulmonary valve
stenosis or insufficiency
Patent Foramen Ovale
Ventricular septal perforation,
myocardial infarction, heart failure models
Atrial/ventricular septal defects
Dilated/hypertrophic/restrictive
cardiomyopathy
Atherosclerosis
Ophthalmology
Wet age-related macular degeneration
model
Retinitis pigmentosa models
Orthopedics
Spinal cord injury animal model
Bone defect model
Fracture model
Neurological Diseases
Alzheimer’s disease
Depression/anxiety
Parkinson’s disease
Epilepsy
Cerebral ischemia and necrosis diseases
Spinal cord injury
Multiple sclerosis
Urinary System Diseases
Surgically induced renal injury
Prostate hyperplasia
Metabolic Diseases
Hyperlipidemia
and atherosclerosis model
Obesity
model
Diabetes
model
Hyperuricemia/gout model
Diabetes and complications
Tumors
Subcutaneous tumor xenograft model
Hematologic tumor model
Glioma model with intracranial
long-term catheter placement
Orthotopic tumor model
Dermatology
Trauma model
Burn/scald model
Systemic lupus erythematosus
Infectious Diseases
Various bacterial and viral infections
